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Lower incidence of fitness CMV infection and acute rejections with valganciclovir prophylaxis in lung transplant recipients. Cytomegalovirus (CMV) is the most common opportunistic infection following lung transplantation. CMV replication in the lung allograft is described as accelerating the write an essay development of bronchiolitis obliterans syndrome (BOS). Essay. Finding a strategy to prevent CMV infection is an important issue. We performed a retrospective, single-centre study of child observation development 114 lung transplant recipients (LTRs) who underwent lung transplantation from January 2001 to December 2006. Fitness Essay. In a smaller cohort of 88 CMV seropositive (R+) LTRs, three months of valganciclovir prophylaxis (2004-2006) was compared to red from green meloy essay, three months of oral ganciclovir (2001-2003) with respect to fitness essay introduction, the incidence of CMV infection/disease, the severity of CMV disease, acute rejection, BOS-free 4 year survival and 4 year survival. In the whole group of good teachers essay 114 LTRs the impact of fitness CMV infection on long-term survival (BOS free 4 year survival and 6 year survival) was assessed. For the cohort of 88 CMV seropositive LTRs, the incidence of writing ideas CMV infection/disease at one year was lower in the valganciclovir group compared to the ganciclovir group (24% vs.
54%, p = 0.003). There was a tendency towards reduced CMV disease, from fitness introduction, 33% to 20% and a significant lower incidence of asymptomatic CMV infection (22% vs. 4%, p = 0.005). A lower incidence of acute rejection was observed in the valganciclovir group. However, there was no significant difference between the two groups in BOS free 4 year survival and 4 year survival. For the entire group of 114 LTRs, BOS-free 4 year survival for recipients with CMV disease was (32%, p = 0.005) and among those with asymptomatic CMV infection (36%, p = 0.061) as compared with patients without CMV infection (69%). Teachers Essay. Six year survival was lower among patients with CMV disease, (64%, p = 0.042) and asymptomatic CMV infection (55%, p = 0.018) than patients without CMV infection (84%). A lower incidence of essay introduction CMV infection/disease and acute rejections was observed with valganciclovir (3 months) when compared to oral ganciclovir (3 months).
The long-term impact of red from green maile meloy essay CMV infection/disease was significant for BOS-free survival and essay introduction survival. Electronic supplementary material. The online version of red from maile this article (doi: 10.1186/1471-2334-13-582 ) contains supplementary material, which is available to authorized users. Cytomegalovirus (CMV) is the most clinically significant opportunistic infection that can occur following lung transplantation (LTx). The reported incidence of CMV infection/disease ranges from 38% to 75% in lung transplant recipients (LTRs) in essay, the absence of writing any prophylaxis [ 1 ]. In addition, CMV infections can have indirect effects; such as allograft rejection, diminished graft and introduction patient survival as well as a predisposition for observation essay, opportunistic infections and malignancies [ 2 , 3 ]. Essay. Finding strategies to prevent CMV infection/disease is a major challenge following lung transplantation. In a previous study of 187 LTRs we reported that oral ganciclovir (GCV) prophylaxis for 3 months delayed the science driving onset and reduced the severity of CMV disease when compared to intravenous (IV) ganciclovir for 4 weeks [ 4 ]. Today, IV GCV followed by VGCV or VGCV alone are the most common prophylaxis strategies [ 5 ]. However, there is essay, no consensus on the optimal duration of prophylaxis for LTRs. Valganciclovir is science coursework driving, a prodrug of ganciclovir with greater bioavailability (60%) than oral GCV (6%) and oral GCV 1000 mg t.i.d.is equivalent to VGCV 450 mg daily [ 6 ]. The main cause of long-term morbidity and fitness introduction mortality in LTRs is bronchiolitis obliterans syndrome (BOS) that is science news coursework drink, present in 49% of recipients 5 years after lung transplantation and at 10 years the introduction rate reaches 75% [ 7 ]. BOS is a chronic allograft dysfunction/chronic rejection that is defined as a progressive airflow obstruction not explained by acute rejection, infection or other confounding complication [ 8 ]. CMV replication in lung allograft is described as accelerating the creative ideas development of BOS [ 9 , 10 , 11 , 12 , 13 ]. The aims of this study were to compare 3 months of CMV prophylaxis using oral ganciclovir with 3 months of valganciclovir with respect to incidence and severity of CMV disease and to study the impact of CMV infection/disease on long-term outcomes/survival. Patient population and study design. Medical records on patients transplanted between January 2001 and December 2006 were reviewed.
During the study period 128 lung transplantations were performed. Of these, 117 transplantations in fitness essay introduction, 114 patients were selected for inclusion. Six patients who died within 30 days of observation essay transplantation and five re-transplantations were excluded. CMV infection, acute cellular rejection (AR) and BOS related to the initial lung transplantation were evaluated. Clinical episodes of CMV infection and AR at essay introduction 12 months were evaluated. BOS development was followed annually. Creative Journey Ideas. Follow-up on all patients was complete on January 20, 2011. The primary goal of the study was to compare 3 months of prophylaxis with VGCV to essay introduction, GCV in both the short and long term. An Essay. To exclude the fitness introduction influence of CMV serostatus, only the 88 patients with R + were included in this first cohort. All patients received VGCV or GCV; which was the standard care for water in urdu, CMV prophylaxis to R + . A secondary goal was to assess the impact of CMV infection/disease (regardless of prophylaxis) on the development of BOS and survival. In this part of the study, both R + and R- patients were included to get a larger group (i.e. the second cohort).
This research was approved by the local Ethical Committee at fitness essay introduction Gothenburg University Hospital, Gothenburg, Sweden and it follows the applicable standards set by the Declaration of Helsinki; reference number O 393-01. To identify CMV episodes; clinical parameters such as fever, cough, dyspnoea, hypoxemia and water pollution other clinical signs or symptoms mentioned in essay introduction, a clinical record were recorded as well as results from transbronchial biopsy (TBB) and maile meloy essay bronchoalveolar lavage (BAL) to detect CMV infection, (ie.histopathology with CMV inclusion bodies and IHC analyses with monoclonal antibodies against CMV). Essay. Analyses of CMV replication by water pollution PCR were registered if it was performed, (i.e.in our study quantitative analysis of fitness essay introduction CMV DNA in serum). Results from TBB were collected to an essay in an, exclude or verify acute rejections. Data from regular appointments was also collected to detect CMV infection (for details see the introduction section on postoperative follow-up). Spirometry with FEV 1, to observation physical development essay, annually evaluate BOS development. Induction therapy used antithymocyte globulin (ATG) with an initial dose of fitness 2.0 mg ? 1 followed by child observation physical essay 1.5 mg ? 1. The doses were based on daily CD3-positive T lymphocyte cell counts and were given until the fitness essay introduction concentration of cyclosporine was 350 ng/ml, (in most cases 2-4 doses of ATG). Together with ATG, 500 mg of creative about journey ideas methylprednisolone was given twice the day of transplantation; following surgery 125 mg of methylprednisolone was administered every 8 hours for a total of 3 doses.
All patients received triple immunosuppressive therapy that used cyclosporine (CsA), mycophenolate mofetil (MMF) and fitness essay introduction prednisone. Water Pollution Essay. The dose of CsA was monitored so as to give an initial trough level of 350 ng/ml (0-3 months). This level was tapered to 300 ng/ml (3-6 months) and lastly tapered to 200-150 ng/ml at 6 months. MMF was given in the dose of 1.5 g ? 2/day which was then reduced down to 1 g ? 2/day after 3 months. Introduction. Oral prednisone was initially given at the rate of good teachers 0.3 mg/kg/day (0-3 months). It was then tapered to 0.2 mg/kg/day (3-6 months) and fitness finally tapered to news driving, 0.1 mg/kg/day at 6 months. Fitness Introduction. If MMF was not tolerated it was switched to azathioprine (Aza) at in an hour the rate of 2 mg/kg/day.
For patients with repeated rejection episodes, CsA was replaced by tacrolimus (TAC). Fitness Essay Introduction. The dose of water pollution essay in urdu TAC was monitored to maintain an initial trough level of 25-15 ng/ml (0-3 months). This was then tapered to 15-12 ng/ml (3-6 months) and further tapered to 12-10 ng/ml at 6 months. Fitness Essay Introduction. No or minimal changes were made in the immunosuppressive regimes during 2001-2003 when oral GCV was used as prophylaxis and news from 2004 to 2006 when VGCV was used as prophylaxis. All R + patients were given oral GCV 1000 mg three times a day for 3 months. In December 2003 the prophylaxis protocol was switched to oral VGCV 900 mg once daily for the same period. All D+/R- patients were given oral GCV 1000 mg three times a day for fitness essay introduction, three months together with CMVIG (Megalotect®) 50 E/kg/day on days 0, 7, 14, 35, 56 and 77 after transplantation. In December 2003 the water pollution prophylaxis was switched to oral VGCV 900 mg once daily for 6 months; plus 6 doses of CMVIG over the same time frame as described in the last sentence. The D-/R- patients received acyclovir for prevention of herpes infections.
IV GCV (except to essay introduction, R-) was used if a patient was not able to take oral medication. Doses of child physical all drugs were adjusted for renal function. The treatment for fitness essay, CMV disease and asymptomatic CMV infection verified by a lung biopsy was IV GCV 5 mg/kg twice daily for 10 to 21 days (sometimes longer).Patients with hypoxia also received polyclonal immunoglobulin (Gammagard®) at a dose of 0.5 g/kg every other day until improvement (maximum 5 doses). Patients who did not respond to about journey, GCV or who had severe bone marrow suppression were treated with foscarnet. A control biopsy was performed 4 weeks after the fitness introduction start of good teachers essay treatment. Fitness Introduction. If needed, at least 2 more weeks of IV GCV 5 mg/kg twice daily was added. If CMV pneumonitis was not diagnosed, no further prophylaxis was given. Postoperative follow-up and monitoring. Regular appointments at the transplant unit, with clinical, radiological and pulmonary function evaluation and water pollution essay in urdu surveillance bronchoscopy using TBB/BAL were scheduled ?, 1, 2, 3, 4?, 6, 9, 12, 18 and 24 months after transplantation and essay introduction then annually.
Pulmonary function tests consisted of science in the coursework driving spirometry (forced vital capacity - FVC), forced expiratory volume in fitness essay, 1 second (FEV 1 ), measurements of lung volume (total lung capacity - TLC), functional residual capacity (FRC), residual volume (RV), carbon monoxide - CO uptake (i.e. transfer factor/diffusing capacity) and the single breath N2 test. Water Essay In Urdu. TBB and BAL were also used if infection or rejection was suspected.TBB and fitness introduction BAL were repeated 4 weeks after episodes of about journey acute rejection. TBB samples were used for histopathologic examination including evaluation of acute or chronic rejection, the fitness introduction opportunistic fungus Pneumocystis jiroveci and CMV infection. Creative Writing Journey. Evaluation of CMV infection was performed using immunohistochemistry (IHC) with monoclonal antibodies against CMV. BAL samples were cultured for fungi and bacteria, including Legionella and mycobacteria,
BAL samples were examined microscopically for CMV inclusion bodies, Pneumocystis jiroveci, other fungi and mycobacteria, throughout the study period. From 2001 to 2006 all follow-ups were carried out using the same protocol. Detection of viral inclusion bodies (‘owl’s eye’) or a positive immunohistochemistry (IHC) in essay introduction, TBB and/or BAL together with parenchymal diffuse or perivascular inflammation or CMV DNA detected in serum, but with no clinical symptoms. In addition to CMV infection, at least 1 of the following signs and/or symptoms: subfebrility (? 37.5–37.9°C) ? 1 day, dyspnoea, cough or decreased FEV 1 and/or decreased CO diffusion. In addition to CMV infection, at child observation development essay least 2 of the fitness introduction following signs and/or symptoms: fever ? 38°C for ? 1 day, dyspnoea, cough or decreased FEV 1 and/or decreased CO diffusion or white blood cell count (WBC) 4 ? 10 9 /l or platelet count 100 ? 10 9 /l. In addition to CMV infection, treatment with continuous positive airway pressure (CPAP) or ventilator was required, or had CMV-related mortality. CMV was found in in the drink driving, TBB and/or BAL after 4 weeks or more. Clinical symptoms such as nausea, vomiting, epigastric pain, diarrhoea, abdominal cramps, together with an endoscopically proven ulcer having microscopic mucosal lesions.
If CMV is detected by essay introduction a positive IHC of the biopsy, we define it as a ‘proven’ gastrointestinal CMV disease. If CMV DNA only was found in serum or the biopsy we call it ‘probable’ gastro-intestinal CMV disease. If a patient had severe symptoms from the gastrointestinal tract and pollution in urdu pos CMV DNA in serum, but no endoscopy was performed, we call it ‘possible’ gastrointestinal CMV disease. Fever, leucopenia or thrombocytopenia together with CMV DNA in serum and fitness introduction no other cause of creative writing about ideas symptoms/signs identified. TBB was routinely evaluated morphologically together with immunohistochemistry (IHC) using monoclonal antibodies to identify early and late CMV antigens (Avidin-Biotin Complex Method for IHC Detection). Fitness Introduction. The same IHC has been used during the science news study period.
CMV DNA in serum was analyzed by quantitative real-time PCR. These definitions are based on fitness introduction, a modified version from a publication by Ljungman et al [ 14 ]. The following definitions; the severity of CMV pneumonitis, prolonged CMV pneumonitis and possible gastrointestinal CMV disease are not generally accepted. Write In An. The authors have found the definitions useful when it’s necessary to describe the symptoms more clearly. Bronchiolitis obliterans syndrome ( BOS ) is defined as a baseline of fitness essay forced expiratory volume in 1 second (FEV 1) calculated as a mean of the two best measurements obtained at the 2, 3, 4.5, 6 and 9 month follow-up appointments at writing about the transplant unit following transplantation. This baseline value is used for comparison with FEV 1 values measured later and to essay introduction, calculate a patient’s BOS grade. Red From Green Meloy. BOS grade 1 has an FEV 1 of essay 65-80%, BOS grade 2 has an FEV 1 of 50%-65% and BOS grade 3 and FEV 1 less than 50% of the baseline value. Obliterative bronchiolitis (OB) is the histological correlate of chronic allograft rejection; a peribronchiolar infiltration of lymphocytes, leading to fibrous scaring in science coursework drink, the bronchioles. Acute cellular rejection (AR) was diagnosed using TBB according to the ISHLT pathological scoring system. Fitness Introduction. (A1 = minimal AR, A2 = mild AR, A3 = moderate AR, A4 = severe AR). Cumulative acute rejection score (CAR score) was defined as the cumulative grading of AR ? 1 (e.g. A1 + A1 + A2 = CAR score of 4) [ 15 ]. CAR score /TBB are defined as an green maile essay, individual’s CAR score divided by their measurable TBB [ 11 ].
BOS-free survival in fitness essay, 107 lung transplant recipients related to creative journey, CMV disease. No CMV infection (n = 65), Asymptomatic CMV infection (n = 11), CMV disease (n = 31). BOS-free 4 year survival for fitness essay, patients with CMV disease was 32%, (p = 0.005), for asymptomatic CMV infection 36%, (p = 0.061) as compared with patients without CMV infection (69%). Survival in 114 lung transplant recipients related to CMV disease. No CMV infection (n = 70), Asymptomatic CMV infection (n = 11), CMV disease (n = 33). Six year survival was lower among patients with CMV disease, (64%, p = 0.042) and asymptomatic CMV infection (55%, p = 0.018) than patients without CMV infection (84%). Demographics for observation physical development, the 114 lung transplant recipients in the study. Recipient Age years, mean (range) Donor Age years, mean (range)
CMV serostatus, n (%) R = recipient, D = donor, COPD = chronic obstructive pulmonary disease, CF = Cystic fibrosis, A1AT = alpha-1 antitrypsin deficiency with emphysema, IPF = idiopathic pulmonary fibrosis, PAH = pulmonary arterial hypertension, PH = pulmonary hypertension, GVHD = graft-versus-host disease. Oral GCV versus VGCV for 3 months in 88 R + recipients. Demographics of the 88 CMV seropositive (R+) lung transplant recipients. Oral ganciclovir 3 months. Valganciclovir 3 months. Recipient age years, mean (range) Donor age years, mean (range)
None of the fitness differences were statistically significant. COPD = chronic obstructive pulmonary disease, CF = Cystic fibrosis, A1AT = alpha-1antitrypsin deficiency with emphysema, IPF = idiopathic pulmonary fibrosis, PAH = pulmonary arterial hypertension, GVHD = graft-versus-host disease. Episodes of CMV infection or disease during the first 12 months in 88 CMV- seropositive (R+) lung transplant recipients. CMV infection or disease. Oral ganciclovir 3 months. Valganciclovir 3 months. CMV infection/disease, n (%) CMV disease -Total n (%) Asymptomatic CMV inf., n (%) Prolonged CMV episode, n (%)
Gastrointestinal CMV inf., n (%) Ganciclovir resistance, n (%) Onset of CMV inf/disease, days, a Onset of CMV infection was 62 days after transplantation for one patient who probably had a GCV resistant virus. Two patients had no or inadequate CMV prophylaxis owing to renal failure. Onset of CMV infection for these two patients was 23 days and 32 days after transplantation. Science In The News Coursework Driving. For the remaining individuals in the VGCV group the essay onset of write CMV infection/disease was on fitness, average 168 days after transplantation (range: 147 – 201 days). In our study, 6% (5/88) had CMV infection diagnosed by CMV-DNA in serum. In the GCV group 2 patients were diagnosed with CMV DNA in serum (one with CMV syndrome and the other with possible gastrointestinal CMV disease). In the creative writing about journey ideas VGCV group three patients were diagnosed with CMV DNA in serum (one with an asymptomatic CMV infection and fitness two with CMV syndrome).
From the medical records reviewed we found that 4 individuals in the R + cohort were diagnosed by green maile meloy essay a physician as having gastrointestinal CMV disease. Three had severe upper gastrointestinal tract symptoms and pos CMV DNA in serum; the essay fourth had lower gastrointestinal tract symptoms plus verified CMV pneumonitis. With three exceptions, the onset of CMV infection in the VGCV group was between 147 and 201 days post-transplantation. Two of the development essay three had no or inadequate CMV prophylaxis owing to essay, renal failure (onset of CMV infection was for these two 23 and 32 days post-transplantation) and for the patient with a probable GCV resistant, the write in an hour onset of fitness CMV infection was at 62 days. Drink. Data for the length of CMV prophylaxis was missing for 2 of the persons in the GCV group and for 3 from the fitness VGCV group; the remainder received prophylaxis for a median of pollution essay 89 (GCV) or 90 (VGCV) days. Incidence of acute rejection (AR) at 3 and 12 months. CAR score a , median (quartiles) CAR score/TBB b , median (quartiles) At least one episode of fitness introduction AR grade ? 1, % (n) At least one episode of AR grade ? 2, % (n) At least two episodes of AR grade ? 2, % (n)
Number of TBB, median (quartiles) a Cumulative acute rejection score (CAR score) varied between 0 and in urdu 6 at fitness essay 3 months and maile between 0 and 16 at 12 months. b Cumulative acute rejection score (CAR score) divided by the number of evaluable transbronchial biopsies (TBB). BOS-free survival and survival in R+ BOS-free 4 year survival in R + (both the GCV and VGCV groups) was 30% for patients with CMV disease and 67% for those without CMV infection (p = 0.018). There was no significant difference in fitness essay introduction, long-term outcome (i.e.
4 year survival and coursework drink BOS-free 4 year survival) between the GCV and VGCV prophylaxis groups. In the GCV group 32% (12/37) were diagnosed with BOS (measured with FEV 1 ) or OB (diagnosed by biopsy). Six of these patients died and one was re-transplanted owing to BOS. In the VGCV group 24% (12/51) were diagnosed with BOS/OB. Fitness Essay Introduction. Two of these patients died and 2 were re-transplanted owing to green, BOS. In the GCV group, a total of 27% (10/37) died within 4 years. Fitness Introduction. Six of journey ideas these individuals died of BOS. Two died of malignancies, one of fitness essay infection (not CMV infection) and one of lung bleeding. In the write an essay in an hour VGCV group 20%, (10/51) of the patients died within 4 years.
Two died of BOS, two of essay malignancies and six patients died of infections. News Drink Driving. (One of them died owing to CMV disease). Episodes of fitness CMV infection or disease during the first 12 months in 114 lung transplants recipient (R + and pollution in urdu R-) Demographics are shown in Table 1 . Follow-up for fitness essay introduction, CMV infection was 12 months. The impact of creative about ideas CMV serostatus was essential for onset of CMV infection. The incidence of CMV infection/disease was for introduction, D+/R- 65%, for D+/R + 39% for D-/R + 27% and for writing about ideas, D-/R- 11% (p = 0.03).
CMV disease was found in 29% (33/114) of the study participants. Among those with CMV disease, 4% (5/114) had severe disease, 18% (20/114) moderate disease, 7% (8/114) mild disease. Asymptomatic CMV infection was found in 10% (11/114) and fitness essay no CMV infection was found in 61% (70/114) of the water pollution in urdu study group. In this cohort only 5% (6/114) were diagnosed with CMV DNA in serum. Gastrointestinal (GI) CMV disease was seen in fitness introduction, 8% (9/114) of the study group. Four patients from the high risk group (D+/R-) had proven GI CMV disease. Red From Maile Meloy. One individual from the low risk group (D-/R-) suffered from essay, a primary infection and had a proven GI CMV disease (as well as CMV pneumonitis). Four individuals categorised as medium risk (R+) had possible GI CMV disease. All had one episode of CMV infection/disease except for one who had 2 episodes.
Prolonged CMV episodes were found in 9% (10/114) of the entire study group. In the high-risk group 35% (6/17) had a prolonged CMV episode. Long-term follow up in 114 lung transplant recipients (R + and R-) according to the development of CMV infection. BOS-free survival in the total group (R + and R-) BOS-free 4 year survival (i.e. patients living without BOS 4 years after lung transplantation) was for patients with CMV disease 32%, (p = 0.005), for red from meloy, asymptomatic CMV infection 36%, (p = 0.061) as compared with patients without CMV infection, 69%, see Figure 1 . Essay Introduction. BOS data was available for 107 of the creative writing ideas 114 patients. All patients were followed with regular function testing (FEV 1 ) for the entire four years (or until death). BOS-free survival was on the average 2.9 (95% CI; 2.6-3.2) years for essay, the total group. Patients without CMV infection were free from BOS for 8.4 months longer than those with a CMV disease/infection.
Patients with D+/R- had the shortest time until the in the news drink driving detectable onset of BOS. Survival in fitness essay, the total group (R + and R-) Six year survival was lower among patients with CMV disease, (64%, p = 0.042) and asymptomatic CMV infection (55%, p = 0.018) as compared with patients without CMV infection (84%). Six year survival for the entire group of 114 patients was 75% see Figure 2 . No patients were lost to follow-up tracking. Four of the 11 patients with asymptomatic CMV infection died early - 2 of malignancy, 2 of infection (not CMV infection). Good Essay. The deaths of 4 out of 11 may at fitness essay introduction least partially explain the maile meloy apparently poor responses among the study participants with asymptomatic CMV infection. Two patients were treated with foscarnet. One had a proven GCV resistance (mutation in the CMV UL 97 gene).
The other had a rapid response after being switched from fitness essay introduction, ganciclovir to foscarnet but no resistance test was performed. Pollution. CMV serostatus for essay introduction, these two were D+/R- and D+/R + . Oral prophylaxis with VGCV seemed to be more effective than GCV among the LTRs studied. A lower incidence of CMV infection/disease at green meloy one year was observed, 24% versus 54% (p 0.003), mainly due to introduction, a reduction of asymptomatic CMV infection from 22% to 4%. Montforte et al performed a similar study comparing 120 days of water pollution in urdu VGCV to essay introduction, GCV prophylaxis in physical development essay, LTRs and they found a lower rate of CMV disease in the VGCV group, 16 versus 8%, but the difference did not reach statistical significance [ 16 ]. Introduction. There was no difference in science in the driving, the rate of asymptomatic CMV infection. In their study regular monitoring by shell vial or CMV antigenemia assay was performed while in our study we monitored frequently with surveillance TBBs including IHC diagnosis. Only a few patients were diagnosed with CMV infection/disease solely on the basis of positive CMV DNA in introduction, serum. Monitoring of blood, today mostly done by molecular assays, might lead to earlier detection of asymptomatic CMV infection which enables treatment and prevention of CMV disease. Our extensive use of surveillance TBBs could also be a contributing factor to physical development, our higher rate of tissue-invasive CMV disease. There was no difference between GCV and VGCV treatment regarding the essay time for onset of pollution essay in urdu CMV infection/disease or the fitness introduction number of teachers essay prolonged CMV episodes.
The rate of gastrointestinal disease, 4-5%, was also similar in the groups. Essay. Gastrointestinal CMV may be underreported in our study since patients with verified CMV pneumonitis treated with IV GCV who at the same time had gastro-intestinal symptoms were not regularly undergoing an endoscopy. Our centre uses ATG as induction therapy, which is supposed to child development, give a higher rate of CMV disease. Essay Introduction. However, the water essay monitoring with CD3-positive T-cells has made it possible to reduce ATG by 50% as compared to our previous fixed dose of fitness introduction ATG, why it now should only have limited effect on the rate of CMV disease. We found that CMV disease was still 20% at 1 year with VGCV prophylaxis for 3 months.
It may be possible to pollution, further reduce this rate with a longer prophylaxis and frequent monitoring with quantitative CMV PCR after cessation of VGCV prophylaxis. CMV prophylaxis after lung transplantation varies widely between centres; most follow a regimen that has 3-6 months of prophylaxis with IV GCV or VGCV with or without CMVIG [ 5 ]. Recent studies recommend extending prophylaxis for LTRs [ 17 , 18 , 19 , 20 , 21 , 22 ]. Palmer et al had less CMV disease with VGCV administered for 12 months when compared with 3 months (4% vs. 32%, p 0.001) [ 21 ]. In our study the fitness introduction frequency of ganciclovir resistance based on treatment failures when using IV ganciclovir was 2% (2/114). Essay. As we did not routinely use CMV DNA detected by PCR during the study period, GCV resistance may have been underreported. As only two patients needed treatment with foscarnet instead of introduction ganciclovir it is also possible that regular monitoring with quantitative CMV PCR would not necessarily have meant that more recipients with GCV resistance would have been identified. In The News Drink. The overall incidence of fitness antiviral-resistant CMV in green maile meloy essay, LTRs has been reported to fitness introduction, be 6-9% and in high-risk groups (D+/R-) 10-27% [ 23 , 24 ]. We found a significant decrease in the rate of write in an hour acute rejection in the VGCV group; at fitness 3 and 12 months.
Between 2001 and science news driving 2006 there were few if any changes in the immunosuppression protocol used by our centre and the significant reduction of acute rejections in the relatively small VGCV group is therefore an important observation. One explanation as to why the AR rate decreased could be that the significantly lower incidence of CMV infection/disease during the first year post transplant among those receiving the VGCV prophylaxis represented less inflammatory response in the transplanted lung(s); which then triggered fewer episodes of fitness essay introduction AR. Paraskeva et al observed a significantly lower incidence of acute rejection within the first 12 months when VGCV for 5 months was compared with GCV for 3 months when there was no difference in physical, the immunosuppression protocols between the two groups [ 13 ]. Jaksch et al found that there was a non-significant positive trend towards a lower acute rejection score when D+/R- LTRs received 12 months of VGCV when compared with 3 months [ 20 ]. Cumulative acute rejection score (CAR) score is not used universally but many authors have found that it is a useful tool for fitness, measuring and assessing combined severity and frequency of rejection over time. CAR score and CAR score divided by the number of essay in urdu evaluable TBBs has been used elsewhere and fitness reported in other studies [ 11 , 13 , 20 , 25 ]. We found a tendency towards lower BOS/OB with VGVV prophylaxis (24% vs. 32%). Since our sample size was small; we believe that it was hard to reach significance. Development of BOS is believed to be an essay, ongoing immunological process triggered by various factors as frequency and severity of fitness introduction acute rejections, CMV infection, other infections, differences in HLA antigens between donor and recipient as well as other inflammatory processes [ 8 ]. CMV infections usually occur during the first year post transplantation, it’s therefore not surprising that when we compared BOS-free 4- year survival after transplantation in creative journey, R+, we found no significant difference between the treatment regimens considering the limited study population.
The effect on development of BOS associated with CMV infection/disease as such could be regarded as the negative impact from CMV infection/disease is stronger than the difference in impact between the two drugs, it’s therefore not surprising that greater BOS development is noted for CMV infection/ disease as such compared to introduction, the effect caused by the difference of the drugs. BOS-free 4 year survival for R + individuals was 30% for those with CMV disease and 67% for those without a CMV infection. To better evaluate the green meloy impact of CMV on BOS progression we included R- to give a larger study group. We found that BOS-free 4 year survival for the total group was 55% and it was lower for those with CMV disease (32%) compared to the 69% rate for those without CMV infection (p = 0.005). Our results support the idea that CMV infection is a risk factor for onset of fitness essay BOS. Other studies have pointed out that CMV infection is physical development essay, one of the fitness essay introduction reasons for development of teachers essay BOS [ 9 , 11 , 12 , 13 , 17 , 19 , 26 ] yet other studies did not find that CMV infection had any impact of the onset of BOS [ 27 , 28 ]. The survival after 6 years (in R + and R-) was 64% for those diagnosed as having CMV disease (p = 0.042), 55% for those with an asymptomatic CMV infection (p = 0.018) when compared with patients without CMV infection (84% survival). The strength of our study is the long-term follow-up, verification of CMV diagnosis by using frequent consecutive surveillance TBBs (including IHC for CMV), and the uniform evaluation and treatment process achieved because Sahlgrenska is a single centre. FEV 1 was followed for the entire four years. No or minimal changes were made in introduction, the immunosuppressive regimes during the period 2001-2006.
The definition of CMV was identical throughout the study period. A limitation is that different CMV prophylaxis drugs were studied during different periods of time. An Essay. Another is that quantitative CMV DNA in serum was not used regularly during the fitness essay study period. Monitoring was performed with TBB/BAL whereas frequent monitoring with molecular assays would have diagnosed CMV infections earlier. Confounding factors with the potential to reduce the CMV infection rate may have included more frequent use of tacrolimus towards the end of the study period - although we do not believe that this affected our findings. Another limitation is that data for immunosuppression was not collected for each patient. In the VGCV group a few more double lung (DL) transplants were included – this may have brought about a lowered development of BOS and improved survival. We observed a lower incidence of red from meloy essay CMV infection/disease and acute cellular rejection during VGCV prophylaxis when compared with oral GCV – both being administrated for 3 months. CMV disease/infection was 24% in the VGCG group and this rate needs to be reduced further. No significant differences were found in BOS-free survival or survival between the regimens after 4 years.
The impact of CMV infection/disease in the total group (regardless of CMV serostatus and prophylaxis) was significant for BOS-free 4 year survival and introduction 6 year survival. This study was financially supported by Agreement Concerning Research and Education of Doctors, The Goteborg Medical Society and Inger and Per-Ake Svenssons Foundation. The authors declare that they have no competing interests. IJ participated in the design of the study, reviewed the medical records, evaluated CMV infection, the severity of CMV disease and drafted the manuscript. Essay. GM reviewed the medical records, evaluated FEV 1 and BOS grade. SN is a statistician and was responsible for fitness essay, the statistical analysis.
UN collected critical data, including donor CMV serostatus and date of death, and assisted in collection of the other clinical data. RA and GM participated in the design of the study and reviewed the creative writing ideas manuscript. All authors have read and approved the final manuscript. This article is published under license to BioMed Central Ltd. Fitness Essay. This is an open access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the observation physical development essay original work is fitness introduction, properly cited.
Inger Johansson 1 Email author Gunnar Martensson 2 Ulla Nystrom 3 Salmir Nasic 4 Rune Andersson 1 1. In An Hour. Department of Infectious Diseases, Sahlgrenska Academy University of Gothenburg Gothenburg Sweden 2. Department of Respiratory Medicine, Sahlgrenska Academy University of Gothenburg Gothenburg Sweden 3. Transplant Institute Sahlgrenska University Hospital Gothenburg Sweden 4. Research and Development Centre Skaraborg Hospital Skovde Sweden. .RIS Papers Reference Manager RefWorks Zotero. .BIB BibTeX JabRef Mendeley. .RIS Papers Reference Manager RefWorks Zotero. .BIB BibTeX JabRef Mendeley. Over 10 million scientific documents at your fingertips.
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Health & fitness essay - A-Level Physical - Marked by…
ot student resume Upon several occasions throughout your career you will need to provide your potential employer with important information about your background and your qualifications. Fitness Essay! The most common method to green provide information to potential employers is to create a resume. A resume can create a vivid word picture of yourself. The World Wide Web (WWW) has recently became more popular, and fitness introduction is often considered the creative writing about, newest form of introduction popular media by many people. In fact, making your resume available on the World Wide Web is comparable to broadcasting it on national television during prime time hours. The most obvious benefit you will immediately receive by making your resume available on the Web is that you will reach an good unlimited number of people and have opened new doors to audiences you would otherwise probably have never reached before. Many companies will visit college resume lists searching for potential employees.
If you have your resume on paper but not on the Web, they will undoubtedly never see it. Another benefit of creating an electronic resume is cost. Many colleges provide space on their web server for their students' resumes free of charge. Fitness Essay Introduction! Using college web servers, students can practically eliminate paper and printing costs. An Essay In An! Rather than performing mass mailings of your resume, you can reduce the number of printed copies you will need and reserve these for companies you are particularly interested in. Fitness! Other benefits you will receive by creating an HTML resume include: the ability to provide electronic links to water in urdu your reference and fitness introduction previous employers as well as providing links to previous jobs or projects you have been involved with the ability to observation physical make updates immediately available ease of fitness essay maintainability the ability to show that you can adapt to, and an essay in an hour use new technology as it becomes available (a plus to many employers) simply making your resume look more professional.
By creating your resume using HTML and making it available on the World Wide Web, you will improve your chances of getting a job that best suits your interests as well as your employer's interests. Writing Your Resume in HTML Format. CREATE YOUR RESUME ON A WORD PROCESSOR AND PRINT IT. When writing your resume, consult English books, writing guides, or take advantage of career services provided by many universities. Be sure to have someone proofread and review your resume. Fitness Introduction! Many instructors in the English department of red from maile essay a University will gladly proofread your resume, but be sure to fitness introduction give it to him/her enough in advance to child provide enough time to review it and fitness so that it will not be an inconvenience to writing about ideas him/her. Remember to be courteous and thank them; after all, they are doing you a big favor. It is much better to have a professor see your mistakes while you have the fitness, chance to correct them than for a potential employer to see them. It is important that your resume be grammatically correct as well as in the correct format.
Your resume is often the first impression an employer will receive. It will be easier to htmlify your resume if you have already created it. By creating your resume first you can focus on formatting it rather than trying to write in an create it and fitness format it at the same time. SAVE YOUR WORD-PROCESSED RESUME IN TEXT (.txt) FORMAT. This can usually be done by using the save as option found under the creative writing journey, file utilities of your favorite word processor.
If you are unable to locate a save as feature for fitness, your word processor consult your user's manual or contact customer support. After selecting save as choose text or Ascii text from the available list of essay in urdu formats. By saving your resume in text form, you will be able to add HTML formatting tags more easily. Essay Introduction! Although you could save your file in other formats, saving in text format will make it easier to edit because text file format does not save any formatting information. Other file formats embed formatting information like boldface, italics, and indentations as part of the file. In The Drink! When you view or edit word processor formatted files you will see formatting information that is introduction, unreadable by HTML browsers, thus you will need to about journey delete it before you will be able to proceed. Editors allow you to change files without embedding formatting options such as boldface, italics and underscoring into the file. Many editors are available to use. Some of the most common are: edit on DOS machines and PCs; emacs and introduction vi on UNIX workstations; and edit on VAX/VMS machines. You can also use your favorite word processor to open a text file.
For more information on water essay in urdu the editor you will use, consult your system administrator or read your user's manual. Which editor you should use depends upon the type of system you are using and your preference between the editors on your system. Make sure you use an editor that you are familiar with. By using an unfamiliar editor you will find yourself spending most of your time trying to learn to use the fitness essay introduction, editor rather than actually creating your resume. Throughout the remainder of good essay this document I will base the essay, steps on creative journey ideas the DOS editor and a generic word processor. To open your resume, first open the editor by typing edit at a DOS prompt, or the appropriate command for the editor you intend to use. Introduction! Next, choose the science in the news coursework drink, Open File option from the FILE menu. Fill in the filename you choose earlier or use the browse feature to locate the fitness essay, file. Elements of an HTML document are denoted using HTML tags.
An HTML tag usually consists of a left angle bracket ( ). Tags are also usually paired (e.g. ltP and lt/P), the first is used to identify the beginning of the element and the second (usually lt/tagname) identifies the child essay, end of the element. Some tags may also contain additional information. This information should be placed inside the angle brackets. For example, to display a paragraph using full justification use ltP ALIGN=justifygt. HTML documents have a minimum requirement of tags. Introduction! These tags are required by HTML browsers in order to recognize a file as a HTML file. The following is water essay, a summary of the required HTML tags: The required HTML tags must be placed in the appropriate order inside and HTML file. The following HTML is a simple example of the minimum HTML document.
Using indentation can greatly improve the looks of your HTML, make it easier to read, and introduction make it much easier to in an hour maintain. Although indentation is essay introduction, not required, you should always use it to improve your HTML. The benefits greatly outweigh the writing journey, extra time it takes to introduction write your HTML. HTML browsers ignore extra white-space therefore the indentation will not be visible when the document is viewed using a HTML browser. Good! Here is the fitness introduction, previous example written using indentation to make it easier to read. ADD ADDITIONAL HTML FORMATTING TAGS AS NECESSARY. The use of additional HTML tags will greatly enhance the good essay, appearance of your resume. HTML contains numerous tags to use, in addition many new tags will be added in the future. Essay! I could not possibly cover every tag here. However, I will briefly describe some of the commonly used and good essay most useful tags. For advanced options, or a more detailed list you should obtain a copy of the latest HTML reference manual.
This manual can be found on the world wide web at essay introduction http://www.sandia.gov/sci_compute/html_ref.html. The following table contains many of the most common and most useful HTML tags. Red From Maile Meloy! You can use any of these tags by simply placing the begin tag, the text to format, and the end tag directly in your HTML document. You will find it useful to view your document as you make changes. See step 9 for instructions on how to view your current HTML document. By doing this, you will become familiar with the effects of the tags. In order to ensure no word processor formatting options are saved into your file you should save your resume as a text file. However, when you choose your filename you should give it the .html or .htm extension. To do this choose save as from the file menu. Next you should choose the text or ASCII text format from the available format list. Finally, type your filename in the filename input box as filename.html or filename.htm where filename is the name you wish to fitness call your file (e.g. resume.html).
CREATE AND/OR ACQUIRE ANY IMAGES YOU WANT TO USE IN YOUR RESUME. While creating images can be very fun and exciting, it is also very time consuming. There are many tools available to help you create your custom images such as Paint Shop Pro, Photoshop, Corel Draw, and MsPaint. For information on how to use these tools you should consult your user's manual. An alternative to creating custom images is to find a non-copyrighted image on teachers essay the world wide web and copy it.
One method of locating useful and free images is to view clipart collections available on the web such as Caboodles of Clipart. Another method of locating useful images is to use the essay introduction, Yahoo search engine and search for the image. To do this simply type image:keyword in the Yahoo's search box and click on the search button. This type of searching is teachers, very time consuming and often does not result in any useful images. If you are unable to create or locate the image you desire and feel that your resume would be incomplete without it, you should consider hiring a Graphics Artist to create the image for essay introduction, you.
Although images can improve the news, appearance of your resume, you should use them sparingly. Often the quality of your resume decreases proportionally with an increase in the number of images you add. Any graphics you use (except for a background) should be relatively small in size. Most web developers agree that large images take longer to load and will in turn drive impatient viewers away from fitness introduction, your page. About! In addition, you should keep the content of your images on fitness introduction a professional level unless the image directly relates to your job qualification.
For example it is acceptable to have cartoons you've created on red from green maile essay your resume if you're applying as a cartoonist. Introduction! However, you should consider placing any such images on a second page and creating a link to red from green meloy essay it. ADD HTML IMAGE TAGS AS NECESSARY FOR EACH OF THE IMAGES YOU PLAN TO USE IN YOUR RESUME, AND SAVE YOUR RESUME (SEE STEP 6). To insert an image into your HTML resume open your resume in your editor, then use the ltIMG SRCgt tag to specify the location and filename of your image. Fitness Introduction! For example, to display an image called computer.gif that is 32x45 in good teachers, size, use the following tag: ltIMG SRC=directory/computer.gif ALT=Computer WIDTH=32 HEIGHT=45 BORDER=0gt. All images should be in the .GIF or .JPG file format. If you see a gray box with three small dots in it rather than your image, then the browser was unable to load your image. Possible causes of this problem are: you used an incompatible file format, the image does not exist, you did not specify the correct filename or had a typographical error in the directory/filename, or the file permissions were set incorrectly (UNIX workstations require that you set the file permissions of an image to essay 770. See your system administrator or consult a UNIX reference manual for help with setting file permissions). Be sure to write an essay hour save your resume after you make any changes.
OPEN YOUR HTML RESUME IN A HTML BROWSER. Open your HTML browser by clicking on essay introduction its Windows Icon, or by typing its execution command at the command prompt. There are many browsers available for red from green maile essay, use such as Netscape, Microsoft Explorer, and fitness essay ICOMM. Write In An! Consult your user's manual for essay, help with using your HTML browser. Open your resume by clicking on the Open File option on the File menu. Next, type the filename you choose earlier in pollution essay, the filename input box or using the browse feature to locate the file, then click on the ok button.
Your resume should be displayed in fitness, the browser window. Pollution Essay! Viewing your resume in an HTML browser is an fitness excellent way to ensure the content of your resume. REPEAT STEPS 5 THROUGH 9 UNTIL YOU ARE SATISFIED WITH THE APPEARANCE OF YOUR RESUME. After reviewing your resume in an HTML browser, you should revisit steps 5 through 9 above and make any necessary changes. Once you are familiar with the red from green essay, process of creating a HTML document, most of fitness introduction these steps can be performed as necessary in any order. You should get your resume to a point that you are satisfied with before preceding. In order to ensure that you have not made any mistakes in the uniform resource locator (URL) addresses, you should click on each of the links you've created using your HTML browser.
Links that do not work are nicknamed broken links. Broken links are highly unprofessional and will affect the impression a potential employer has on red from meloy your resume. Broken links are usually the result of a typographical error or a link to a web site that no longer exists. Because the web is constantly changing, you should only create hypertext links to sites that are relatively stable. In order for your resume to be visible to the rest of the fitness essay introduction, world, you must have current internet provider. Many universities provide the resources for students to install their resumes. Contact your University Webmaster to red from essay obtain information.
You can often locate the Webmaster through an fitness essay introduction email address on the universities main web page. Writing! After you have completed your HTML resume, copy it and all of the images you have used to the directory your web provider specifies. After installing your HTML resume you should always test it. Fitness! Visit the green meloy, URL your web provider supplies to insure it was installed properly. You should always respond to potential employers that contact you as soon as possible. In addition you should always mail a paper copy of your resume to introduction any potential employers. By showing sincere interest, you will increase an science news coursework employer's impression. The Source For Java Development. Java Report . Fitness! March/April 1996.
Java Report is a relatively new magazine for software developers using the Java environment. Java is a relatively new software developing environment that allows software developers to water in urdu implement more complex features such as Net-based electronic transactions and delivering interactive content across the Web. Java Report combines programming tips, new technology, application trends and fitness essay corporate issues to bring the reader a broader range of information. In one of the articles Philip David Meese does an excellent job of explaining to the reader how to create his/her first Java application. His article was well written and was equivalent in content to a small course. The article The Java Tutor provides clear and concise information as well as easy to creative writing about journey ideas understand example code. I strongly agree with Mr. Meese's confidant statement by the time you finish reading this article, you'll be able to develop a Java application.
An entire section of Java Report is devoted to Product Review. In this section the authors review Java related products and provide information to the reader. This information was the equivalent of a Consumer Reports article. This section is a great source of fitness information about individual products. In general, Java Report is a great source of information relating to the use and development of Java applications for any software developer. Creative Writing! However, some of the technical articles may be beyond the fitness essay introduction, scope of the average reader.
Rampe, David. Cyberspace Resumes Fit the Modern Job Hunt. The New York Times . 3 February 1997, sec. C6. In his article Cyberspace Resumes Fit the Modern Job Hunt David Rampe discusses the advantages and disadvantages of an HTML resume. Hour! The article, which appeared in The New York Times' Taking In the Sites section provides some very useful information regarding resumes. Some of the essay, topics Mr. Rampe discusses includes the searchability of HTML resumes, electronic filling, industry jargon, and the dehumanization of the write an essay in an hour, process.
Mr. Rampe also discusses the essay, importance of writing your HTML resume in green maile essay, the proper fashion, to the computer. He states that you must resolve mentally to address your resume to essay introduction 'Dear Computer. ' and just ignore the dehumanization of it all. In addition, the article provides the URLs for eleven electronic sources to help the reader get started. Each of the sources listed are excellent sources of meloy information and should be reviewed by anyone who decides to create and HTML resume. Rampe also discusses cookie-cutter forms available on the World Wide Web to fitness help the least experienced computer user create his/her HTML resume. In general, Mr. Rampe provides an ample amount of information and resources necessary to create an HTML resume.
Rampe provides both the pros and the cons of an HTML resume in ideas, an unbiased fashion, leaving the reader to fitness essay introduction decide the necessity of an HTML resume. Sandia National Laboratories. HTML Reference Manual , 2 January 1996. Sandia National Laboratories' HTML Reference Manual is, in development, my opinion, the most complete and useful source of HTML information. Although the manual is currently over fitness essay, a year old, the green, information it contains is accurate, precise and very helpful.
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This document is an science drink excellent source of information for both the fitness essay, novice and expert HTML programmers. Authors Note: Windows, DOS, Paint Shop Pro, MsPaint, Yahoo, Café, Netscape, ICOMM and Microsoft Internet Explorer are copyrighted by their respective owners.
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+30 Best Examples of fitness, What Skills to Put on a Resume (Proven Tips) Meet Jane. Jane is the CEO of Jane’s Addictive Sweets. She makes cupcakes. You like cupcakes, and you want to work for write an essay in an hour, her. How does Jane know that you are the person she’s been waiting for all her life?
A list of fitness, skills to put on a resume is as important as icing on red from green essay a cupcake. No one wants a cupcake without icing. No one. So, if you want a resume that will give you more interviews, you need to know what skills to put on essay introduction a resume and how to describe them. This article will show you: Where to good put work skills on a resume. What skills to put on a resume to get you MORE interviews. How to list work-related skills on a resume. Fitness Essay Introduction? 31 best examples of creative writing about journey, how to put your skills on a CV ( right vs. wrong examples). INFOGRAPHIC that shows the most important resume skills. If you have any questions about essay introduction, your resume skills, make sure to ask in a comment - I will be happy to answer.
What to Put on a Resume to Make it Stand Out. Apart from write an essay experience and education, you should consider putting your achievements, a resume summary, and key skills on your resume to make it stand out. This article will show you how to put key skills on your resume. Here's an example of the wrong and the right way to introduction put skills on a resume. Want to essay save time and have your resume ready in 5 minutes? Try our resume builder. Introduction? It’s fast and easy to science coursework driving use. Essay? Plus, you'll get tips while writing your resume. See templates and create your resume here. Good Essay? As you can see, the resume skills section and the resume summary are the most visible sections . Essay Introduction? That's because skills and qualifications are what employers look for , so these two sections should immediately grab the attention of the hiring manager. What are key skills for your resume?
Key skills are work-related skills that you need to do a job. Most often, you can find key skills in job descriptions. Where do you put skills on a resume? Skills are so very, very important that they should show up all over your resume. Not just in the resume skills section. But, you do need a professional skills section, and it should be in a prominent place on good a resume. You can also try putting your skills section in a side column. Also, make sure that a couple of your key skills appear in introduction your resume summary (here's how to do that) and cover letter (read more) . Several should show up in your experience section. Sprinkle a couple through your education section. One of the reasons you will want to do this is something called Applicant Tracking Systems (ATS). More about red from meloy, that later.
What Skills to Put On a Resume - Hard and Soft Skills. First, you need work-related skills. Not bow hunting skills or nunchuck skills. Real career skills. Fitness Essay Introduction? So, what are the best skills for green maile meloy essay, a resume? Okay, the first thing you need to know is that there are two different types of skill sets - hard skills and fitness essay, soft skills. Hard skills are not “skills that are hard to learn.” They are the technical skills and abilities you need to do a specific job.
For example, say you are applying for the position of dump truck driver. So, being able to drive is most likely the top hard skill you need to have to do the job. Typical hard skills to list on a resume include things like computer skills or driving a dump truck. A hard skills list is especially important for an essay, professions such as engineering, IT, and medicine. Here's a list of 10 typical hard skills to include on a resume: Data Analysis Copywriting Foreign Languages Accounting Computer Languages Mathematics Graphic Design Planning / Event Planning SEO / SEM Marketing Bookkeeping. A common way to describe soft skills is to call them “people skills” or “social skills.” Soft skills are often linked to personal qualities that make up a person’s “emotional intelligence.” They are special skills like communication, relationship building, and creativity. Fitness Essay Introduction? List of 10 soft skills to include on a resume. See examples of how to describe them. Communication Ability to Work Under Pressure Decision Making Time Management Self-motivation Conflict Resolution Leadership Adaptability Teamwork Creativity. The difficulty of teaching and defining soft skills for a job is the reason why a list of soft skills on an essay a resume are valued. And if you have great soft skills on your resume , you will do better than a candidate who has nothing more than the required technical skills.
For example, research by the National Association of Colleges and fitness, Employers (NACE) shows that the key resume skills employers favor in an essay new college graduate applicants aren’t the technical types of essay introduction, skills for red from meloy, a resume . So, what skills are the best to put on a resume? The most desirable skills for a resume are leadership and the ability to work on a team, with 77.8% of introduction, employers searching for both of these key skills among new college graduate hires. Only 67.5% of employers will look for “technical skills.” So, when an employer must choose between two applicants with identical technical skills, the candidate that has proven leadership skills (or other types of soft skills) has a better chance. Sounds like becoming team captain of your lacrosse team as soon as possible is write an essay a good idea. Fitness Introduction? First, you need to choose the good essay, best skills for your resume. This is the fitness essay introduction, most daunting part of adding a resume skills section. It may seem simple, but take a look at the following example: I know how to use a computer.
It’s a good hard skill. So I add “computer skills” to the bullet point list at the end of the resume. That’s great. Got it. But if you want to be more thorough, here are six easy tips to follow in order to make sure you have ALL of the good skills you need.
So how do you decide which skills to put on your resume? I'll show you how, but first - always remember to put your skills front and center . Here's an example of a template from our resume builder that properly showcases skills on a resume. 1. How to Make Your List of Job Skills Relevant to observation the Job Offer. Essay? What skills are relevant for a resume? Let’s put it this way. If you’re applying for a position as a Marketing Manager, your ability to tie a cherry stem into teachers a knot with your tongue is irrelevant. Proficient with Customer Relationship Management (CRM) software (Salesforce). Tying cherry stems into fitness essay introduction knots. Maile? If you're changing your career from Sales Associate to fitness essay introduction Customer Service Representative, most of your Sales skills will become irrelevant. In that case, you'll want to make a list of abilities from your sales job that count as customer service skills on a resume. A good start is to make a master list of job skills and professionals strengths before matching them to business skills listed in the job description.
Take a moment to water pollution think about all of the awesome things you can do. Make sure most of introduction, them are things to put on a resume. If you're stuck, start with a general list of abilities as a warm up and then make a list of meloy essay, skills to fitness add to a resume. Which of write an essay in an hour, these things could be your hard skills? Can you prove them? Which of these could be your soft skills? Again, can you prove them?
Are you a good listener? That’s a great soft skill. Can you use Microsoft Word? That’s a very basic hard skill. Here is a sample of what a typical resume skills section might look like: Speak and write in fluent Spanish. Proficient in Microsoft Office including Excel and Powerpoint.
Working knowledge of WordPress. Able to manage and implement Social Media campaigns. Excellent written and verbal communication skills. Excellent editing skills. Able to introduction translate complex text into easily readable material. Maybe you have some of these key skills . Maybe your skill set is completely different. Water In Urdu? We’ve put together examples for you ( see below ) to help you brainstorm so you don’t leave out any of your best skills for a resume. Introduction? Next, match your list to the resume skills listed in the job description. All of the red from maile meloy, personal skills and talents you have can fall into one of fitness essay introduction, three categories: Transferable Skills - the definition of transferable skills are key skills that you can take with you from one job to another. Examples: Microsoft Excel or Phone Etiquette Job-related Skills - job-related skills are the specific skills you need to essay do a certain job. Examples: Scuba Diving or Java Programing Adaptive Skills - adaptive skills are personal attributes or skills you use to survive life.
Examples: Persuasion or Confidence. Why is this important? Because there are different ways to essay put work-related skills on your resume depending on which category they fall under. News Driving? Step 1: Go through the job description to find the job-related skills that are required for the position. Step 2: You should have most of these key skills.
Otherwise, you won’t be able to do the job. Essay Introduction? For this job, you need to be able to: Conduct webinars. Attend informal dinner meetings. Speak in front of large groups. Discuss and present software. Teachers? Step 3: These job-related skills should go in your resume skills section and possibly in your resume objective or summary so an employer will see them right away. There should be evidence (work experience, education, training) that prove your ability to demonstrate these key skills on a resume . Pro Tip : You can also put these skills in bold , for example, conduct webinars . Using bold for keywords helps the draw the essay, recruiter's eye while they are scanning, and will make you more memorable as well. Step 4: Next, look for write in an, all of the adaptive and fitness, transferable skills that the employer wants on top of the regular job-related skills. Red From Green Maile? Step 5: Sprinkle proof that you have these types of skills throughout your resume. Add a few with quantifiable proof to your professional skills list.
Adaptive Skills for a Resume. Transferable Skills for a Resume. 2. Research People Who Already Have the Job You Want. Introduction? Once you’ve mined the teachers essay, job description for examples of professional skills to introduction include on your resume, visit LinkedIn for write an essay hour, a little bit of snooping. Why do you want to peep on other professionals? Researching other professionals' strengths will let you know what skills and abilities are already valued in that profession. Add any duplicates of fitness essay introduction, your skills to your resume skills section. Pro Tip : For future reference, you can also check out the courses, certificates, education, and skills sections to unlock new achievements.
Now you know how to take your career to the next level with a similar course or training. 3. What Skills to Put on a Resume for Extra Value. Now ask yourself: Are any of your transferable skills and qualifications missing? Remember transferable skills are the observation, universal skills that translate across jobs - like being proficient in Excel or Spanish. Good skills like Excel and essay, Spanish are always relevant. If you missed any, add them even if they were not mentioned in red from maile meloy essay the job description. 4. Add the Universal Skills That All Employers Want. Essay Introduction? I know I’m getting repetitive: Go back and check one more time to creative writing journey make sure you have EVERYTHING. Remember, most of the unique skills that you put on fitness essay your resume should be job-related skills taken from the job description and your best transferable skills. Adding a couple of child, your best universally desired skills is essay a way of sweetening the deal, but don't overdo it or base your entire resume on these examples of skills. Have a look at our resume skills list.
Do you have any of them? 5. Numbers and Facts Will Make You Stand Out From the Crowd. Now, you're probably wondering how to red from maile essay put skills on fitness a resume to convince the recruiter you’re the best fit? Use facts and good, figures. Forget about introduction, superfluous adjectives. It’s as simple as that. Use proof to persuade to science in the coursework draw recruiter’s attention. 6. Beat the Bots By Adding Keyword Skills. Today, a lot of resumes are read by fitness essay introduction robots before they ever fall into human hands.
That’s right. You worked hard on your resume, but a lot of child physical development essay, hiring managers won’t even bother to look at it before having R2-D2 run a scan on it. Fitness? The software sorts through applicants’ resumes and compares the resume skills you’ve listed to those found in the job description. In An? To pass the inspection, you have to match a certain amount of these keywords. You can visit Jobscan to fitness essay introduction see how well you've matched your resume to creative about ideas the job post. Around 70-80% of the skills on your resume need to match the job description.
Note, the percentage can differ depending on fitness essay individual Human Resource departments. But, you can’t just pack your resume full of keyword skills to trick the bots. TheLadders say that Applicant Tracking Systems (ATS) are now able to child observation contextualize the content of your resume. Fitness Essay Introduction? What does this mean? The software can read your resume almost like a human. That doesn’t mean that keywords aren’t important. Keyword skills should appear throughout your resume. Science News? You just have to make sure that skill sets are added in a way that reflects your full experience learning, using, and working with those key skills.
Pro Tip: You should label your resume skills section “Skills” so that any ATS program can easily identify it. Want more tips? Read our complete guide: 42 Amazing Resume Tips That You Can Use In 30 Minutes [Examples] The Technical Skills That Employers Desire the Most. Introduction? The shift to a technology-based economy has made science, engineering, math, and IT skills some of the most in-demand skills for a resume among employers. So, what are the best technical skills for a resume? LinkedIn made a list of the 25 top hard skills for a resume in 2016 , and good teachers essay, it’s all tech skills. The number one skill was “Cloud and Distributed Computing.” Technical skills are either something you have or you don’t, but they are always something that you can learn. Most people will only be required to have basic technical skills on their resumes like software skills - e.g., the ability to essay use Microsoft Office and Excel. Professional skills on red from green maile meloy a resume are the one thing that will quickly communicate to an employer that you are the right fit for a job.
And after you’ve proven that, the introduction, fact that you have listed universally desirable skills on your resume will put you ahead of the pack. That’s why it is important to: Carefully craft a good skills section for your resume. Place key skills throughout your resume. And now you know how! INFOGRAPHIC - Everything You Need To Know About Your Resume's Skill Section. The infographic featured below will show you the most desirable skills to put on a resume and how to pollution in urdu showcase them. Like the infographic? Feel free to share it or use it on your site. I'll be happy to write a personalized introduction for your blog. What skills should you put on a resume to get an fitness essay introduction, upper hand?
Leave a comment if you have any questions about what skills to put on a resume or how to add them. Natalie is a writer at Uptowork. Writing Journey? She loves writing about resumes and eating tacos more than life itself. Essay? She spends her free time reading complicated novels and pollution essay, binge watching TV series.
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symbols which can be understood and manipulated by someone who is culturally literate. Second, being literate can mean having knowledge or competence. For . Fitness? example, we speak of people being computer literate or politically literate. For your first essay , try to focus on a moment or a period in your life when you realized the red from green maile meloy, significance of fitness essay introduction being literate in water pollution, this fashion. Did you have trouble using a computer to register for classes? Did you fit into a subculture because you learned to speak its.
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