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Business Owner Resume Sample and Writing Guide. Whether you’re a business owner, operations manager, or even a serial entrepreneur, if you’re looking for a job you’ll need a resume. But how exactly do you summarize your extensive experience and leadership success in help write my papwer one short document? We had our professional resume writers create a sample business owner resume to good resources show you how. Write My Papwer? Keep reading to view this expertly written example of a business owner resume. We also provide a writing guide below, explaining exactly how to create each section. Follow this guide and write your own interview-winning business owner resume! Business Owner Resume Writing Guide and Sample. CLICK HERE TO DOWNLOAD THIS BUSINESS OWNER RESUME TEMPLATE.

Have your resume written by a certified writer today! Plans pricing begin at JUST $99 Call for a free consultation 1866-706-0973. Writing a contact details section is relatively straight forward, but be sure to check that you’ve got your phone number and email address correct. You may not need reminding, however this information is essential for a hiring manager to contact you, and mistakes are easily made! Here are some more writing tips: Use hyphen or a period to separate your phone number, making it easier to read. Be sure to include an email address that sounds professional: [email protected] is far more appropriate than [email protected] If you have a LinkedIn profile I recommend including the research paper resources, URL. If you don’t yet have a LinkedIn account, I recommend setting one up. We offer a professional LinkedIn writing service, and you can read our Linkedin guide for essential help and help write my papwer, advice.

We strongly recommend scrapping you Career Objective and replacing it with something different. If you look at the above example of a business owner resume you’ll see it begins with a professional title: Business Management Leader Entrepreneur. Giving yourself a professional title helps build your personal brand as a (in this case) business management leader entrepreneur. A professional title can also be adjusted for each job application you making, matching it to the specific job title that you’re applying for. Singapore? For example, if applying for a Director of help write my papwer Operations position, then you should include this in your resume’s headline.

This helps highlight your expertise and research paper resources, convince the reader that you’re an ideal candidate for the job. #8230;when writing your resume you should keep in mind the specific responsibilities and directives of the position you’re applying for. Engaging the reader early is an write my papwer, essential requirement of letter a business owner resume. If you pique the reader’s interest at the start they are more likely to read the document in full, giving you more opportunity to help write convince them you’re right for the job. Business owners often have extensive experience at many levels, from staff management to business development. Essay? However, the inclusion of irrelevant or non-targeted information can detract from the effectiveness of your resume.

To avoid this, when writing your resume you should keep in mind the specific responsibilities and directives of the help, position you#8217;re applying for. Remember, the person looking to hire you wants to see your ability to excel within the essay competition, role they have to help write my papwer offer. You need to tailor the content of your resume and the experience you present to align with their needs. To boost your chances of success this information must be delivered in a concise, high impact manner. The business owner resume sample above achieves this by including three key summary headlines: Business Regeneration: Transforms struggling businesses into how to write macro successful companies, capturing multi-million-dollar long-term revenue increases by help my papwer implementing strategic plans Operations Management: Boosts revenue and best, performance while mitigating risk by overseeing daily policy and procedure enforcement, employee teams, and financial metrics Entrepreneurship : Identifies and seizes viable opportunities for expansion and innovation and grows them into profitable and write, valued enterprises with loyal customers. Using the space at the top of your resume to demonstrate your key strengths will really help engage the reader. This technique also allows you to marketing yourself and target the specific job requirements. Most of all, this technique increases the how to write macro, overall impact of your resume. Within the first one-third of your resume your goal is to demonstrate exactly why you’re the ideal candidate. An areas of expertise section is a great way to do this.

You’ll see on our business owner resume example that the resume writer cites ten bullet pointed areas of write my papwer expertise, showcasing the applicants diverse skill set in the world of business. You should look to buy cover letter do the write, same thing on greatest, your resume – this is where you can present the help my papwer, range in good resources your expertise and help write my papwer, knowledge. Don’t just match the duties on the job description; analyze the job responsibilities along with the essay, company goals and determine which of your skills are most relevant and desirable. In the business and management world, it’s all about results. Professional resume writers strive to understand not just your work history, but what you achieved in each job. That#8217;s why the most effective resumes are achievement focused this is especially so with business owner resumes. Write My Papwer? Showcasing your achievements and success on your resume is paramount, and you don’t have to be subtle about best buy cover letter doing this. Help Write? That’s why our business owner resume example includes a key accomplishments section. Rosemarie Willett? Also, notice how our resume writer has quantified achievements wherever possible, for example: #8220;#8230; capturing a revenue increase of 70% in help my papwer one year #8220;.

Quantifying achievements helps improve readability, and increases the impact your resume has on the reader. This section doesn’t need to be too lengthy; your goal is to create a concise, easy to read section summarizing your work background. Best? Assuming you’re seeking a leadership position, you should focus on tangible achievements from your work history, illustrating the my papwer, positive affect you had at buy cover each company. Here#8217;s a summary of what and what not to do in this section: Avoid endless lists of write my papwer day-to-day duties and responsibilities Use quantitative data where possible to rosemarie highlight your job role and accomplishments Use active language and help write my papwer, begin each bullet point with an action verb If possible, include a summary bullet point giving scope to best buy cover letter your job, e.g. size of company, annual revenue, number of employees, product/service rendered. Help My Papwer? Don#8217;t include work history from more than 15 years ago. College? Education sections should be kept short, and include the name of the course/qualification you studied and the school attended. If you are concerned about help write my papwer your age then you can leave off graduation dates. If your level of education is likely to competition help earn you interviews then consider putting this section above your professional experience.

If you have industry specific certifications or licenses consider including these in write this section. Professional Memberships Honors and Awards. To keep this business owner resume example within 2 pages long, you can see a clever formatting technique used by essay our professional resume writer. Since these sections have very little information, our writer created a table with two cells and presented both sections side by side. A great space saving technique, and one that allows you to include some subtle coloring, giving a professional looking finish to the document. Have your resume written by a certified writer today! Plans pricing begin at JUST $99 Call for a free consultation 1866-706-0973. Did you find this article useful?

Don#8217;t forget to help like and share by clicking the social tabs below. Have your say share your thoughts and ask our experts a question by leaving a comment below! Get your resume professionally written today! View our plans pricing or call 1866-706-0973. Stay in touch by adding us on a2 biology synoptic questions, your favourite social media!

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Project Manager Resume Sample Ready For You !! A project manager is in charge of projects. A project manager can be found in many different industries, including in management, business, accounting and most often construction. A construction project manager hires and supervises many different individuals including contractors. In construction, project managers are often called construction managers or foremen. Project managers often work for years as other professionals including electricians and carpenters in the past. Now hiring managers typically prefer to hire individuals that have a bachelor degree in construction science, construction management or civil engineering. In other professions including in management, a business professional also prefers to hire project managers with a bachelor degree. Project managers also need a minimum of one to three years of work experience. This may be gained by managing jobs in the industry.

Other key skills include: Interpersonal and help, decision-making skills Strong communication skills Good team building and leadership skills Ability to multi-task. The Bureau of Labor Statistics states that a project manager earns an average median salary of writing competition, $83,860. Top earners can earn nearly $100,000 or more in this industry if working in the construction industry. Typical job duties for construction managers include: Scheduling projects in ordered steps.

Budgeting time to help write my papwer, meet project deadlines. Hiring and supervising personnel for projects. Resolving problems, designing work procedures. Competition Singapore! Preparing work contracts. Making additions to write my papwer, contracts and agreements, working with consultants, clients, vendors, suppliers and subcontractors. Working on designs, technical writing or specifications.

Interpreting plans, contract and other blueprints to other staff including administrative personnel, workers or clients. To earn a job as a project manager, you have to good research paper resources, have a resume that is top-notch. Help! Your resume should reflect your key talents, skills and abilities as a project manager. Best! Here is a sample resume that will help reflect your skills and write my papwer, abilities as a project manager. JOHN C. PROJECT MANAGER. Professional Project Manager with 7+ years’ project management experience in the public sector with emphasis on rosemarie, environmental projects and help my papwer, managing crews, construction and demolition projects. Construction/Demolition Environmental Projects OSHA Compliance Change Management Budgeting Cost Controls Bidding Proposals Crew Supervision. ABC Construction, LLC. Best Buy Cover Letter! (Denver, CO) – Construction Project Manager 2-08 to Present.

Led infrastructure improvements on highways following award of government contract. Q Company, Inc. (Colorado Springs, CO) Site Supervisor, Project Manager 3/05 to 2/06. Helped supervise engineering and crew teams, road projects, restore compliance and adhere to write my papwer, safety regulations on how to macro, new construction. PC Construction Company (Manitou Springs, CO) 3/04 to 3/05. Demolition, improvement projects, compliance and help, maintain OSHA regulations, project management for specific commercial construction projects. University of Colorado – BS in Civil Engineering 1998. OSHA Hazardous Waste Operations Emergency Response Certification. Below is best buy cover letter Another Guide with Sample For You!! Are you a project manager seeking another level of challenge in your career? Do you need to write a compelling resume?

Your resume is the first thing an employer looks at, and it’s your best shot to help, stand apart from the rosemarie, crowd. So, it’s really worth your time to pay more attention and ensure it is distinct. The tasks of help my papwer, project managers are now invaluable for companies in the information age. Consequently, Employers look for some specific qualities in thesis project managers. Most companies seek Project Managers because they streamline production process, and thus save cost, increase ROI and enable companies plan better. You have to bear this fact in mind when writing your resume. For project managers, what really matters to Employers are experience, education, number and size of previous projects, personal skills as well as other accomplishments. Let’s see the things that make a project manager resume compelling as well as the most important areas of emphasis that make the eyeballs of employers pop. What Do Employers Look for write in a Project Manager’s Resume? In a project manager’s resume, employers usually look for greatest college essay specific information to help them decide the my papwer, best hire.

This information includes: 1. Experience that can be verified: Employers want to make sure they can directly or indirectly verify candidate’s experience as specified in buy cover letter their resumes. Here are the things an employer would watch out for: Number and size of the projects you have undertaken in the past: Employers want to know how many projects you have undertaken in the past as well as the size of the project in terms of scope, budget etc Type and complexity of projects: As you know, project managers handle very wide range of tasks. Employers like to know if you have handled similar tasks to help my papwer, the projects in how to their organization.

If not, they would be interested in the complexity of the projects you have handled in the past. Budget, scope and timelines of projects: Employers are interested in write my papwer how you managed the budgets for previous projects, whether you met deadlines or not and the scope of the project Written Communication Skill: This is verified by the way your resume is structured and how your experience is explained in your resume. Similarly, your verbal communication skills will be evaluated during the interview session. Education: Here, employers want to know whether you applied your skills to work and write macro, how you applied them. Help! Results: Employers also want to know whether you achieved success and how. They like to know how you tracked project performance, how your expenses stand against greatest influence college essay, the original budget, matrix management and communications management.

Of course, you can’t spell out all your achievements in detail but the write, few ones you list should be directly related to the organization you are applying to. Paper! Secondly, ensure you specify the number of write my papwer, projects you have handled since you can’t list all of them. Employers are concerned about how many times you have changed jobs and why. This is the only way they can safeguard their organization against good research resources, job seekers that hop from one company to another. 3. Timing of help my papwer, Project Management-Related Credentials. They want to know whether your project management credentials came before your experience or vice versa. How to willett thesis, Write a Project Manager Resume.

Having said what employers actually look out for in your resume, let’s now discuss how to write a compelling Project Manager Resume for those who are just starting a career in project management and those who have lots of experience. This is the most important information in this section. Help Write My Papwer! Employers go through hundreds of resumes; as such, they have limited time to go through your resume. Rosemarie Willett Thesis! So, ensure your resume is concise and clear. Very importantly, your skills and experience should be very noticeable and easy to read. A project manager’s resume should not be unusually over-worded. Employers want to know about you, and they want to do that as quickly as possible. So, any extra word in your resume is limiting your chances of getting the job. Bear in mind that it is more professional to write in the 3rd party. It also helps make your resume more concise. So, your experience should read ‘Pioneered revenue management web-based software for banks’ instead of ‘I pioneered …’ or ‘Smith pioneered …’

It is important to bear this in mind before you start writing your resume. Having correct contact details is help my papwer definitely an obvious need in a resume. Greatest Influence Essay! So, ensure your contact information is updated. Write My Papwer! Check your mobile number and good research, email address, and be sure they haven’t change or you haven’t mistakenly deleted one or more letters. Make sure you use a number that can be easily reached.

If employers find it difficult to reach you, they’ll just move on write, to the next resume. This should be a summary of your past, present and future. Make sure this is good paper really enticing, making employers want to learn more about you. Use very appropriate words to describe your skills, experience and goals. This is what separates the resume of a young graduate from an experienced project manager. Help My Papwer! A young graduate needs to list his or her educational details immediately after the a2 biology, personal profile to make the resume enticing. Particularly, new job seekers should ensure consistency in education progression.

You need to demonstrate the ability to focus, gain qualifications and pursue the same career. Now, your career history should come after your education. For experience job seekers, your career history should come before education. Employers want to see facts and figures – budgets, scope, results, communication management, team management, etc. Include words like ‘Saved over $300, 000 of write my papwer, management cost by … ‘ or ‘ … completed the willett, entire project within budget, with minimal deviations and in time’. After career, an experience project manger should list technical skills.

As said earlier, the career history should come before education for experienced job seekers, whereas it should come after education for new job seekers. Here’s how your career should be highlighted. Your career should be highlighted in write reverse chronological order. That means, your most recent employment should come first and good research paper resources, then followed by write my papwer, the previous one. The important information you should include are company name, job title as well as the dates you started and stopped working there. Usually, the dates should include the months and years, but not necessarily the day. If you have jumped around a couple of jobs, remember to state why you left in just one sentence. This is particularly important for technical project managers – engineering or IT project managers. You don’t have to good resources, list every little thing you know. Instead, focus on the ones you’ll find easy to help my papwer, answer during an interview session.

There are many schools of buy cover letter, thought about the role of hobbies in resumes. Basically, you want to help write my papwer, appear like a disciplined person who can handle the role advertised. Below is a sample resume for an experienced Project Manager. This will serve as your template for writing IT project manager resume, construction project manager resume and greatest influence college essay, others. Jennifer White , PMP, MBA, B Sc Digital Marketing. 25B, Madison Avenue ? Sydney Area, Australia ? 123.456.7890 n [email protected] Systems ENGINEER ? IT Services Deployment ? SOFTWARE Development. Close to 10 years of enterprise-related project management in write customer service, marketing and operations for healthcare, management consulting and retailing environments across public and private enterprises. Information analyst with track record of boosting revenue by over 20% following the write, introduction of new tactics to old systems.

Manage projects worth millions of dollars, taking outsourcing solutions across West Africa, East Africa and environs; completed the help, entire project within budget, in time and with minimal deviations from original plan. Experienced in project management using expert online freelancers across the buy cover, world to help, cut down operations cost by a2 biology synoptic essay, over 40% with smoother operations and greater success rate. Email Encryption Solutions. Enterprise Messaging Solutions. Mobile Payments Implementation.

Enterprise Email Messaging, Project Lifecycle. Budgeting and Cost Analysis. Project Scope Design. Business Modeling Ancillary Skills. Team Building and Management.

Client Relationship Management. DEVANUS INC. (Sydney Area, Australia) May 2002 to help, present. Senior Project Manager, January 2006 to best, present. Oversee the help write, development of influence, interactive, multimedia, Internet-based customer enquiry desk for Airtel largest full service advertising and help my papwer, communication firm. Provide project management for large projects involving complex technology and lead cross-functional teams of up to 20 programmers, developers, and analysts.

Budget = over $10M. Drove up customer satisfaction score by 25% in just 8 months and turned; slashed turnaround time for buy cover customer service desk by as much as 5 days (from 2 weeks) by introducing sms-based customer service support system. Elevated revenue by over one million dollars by using technology to write, identify the most loyal and rosemarie, highest paying customers and then providing specialized service to them Built greater expertise and hence confidence in my papwer staffs by identifying in-house, experienced experts and organizing informal training sessions for new and upcoming staffs. Project Manager, May 2002 to January 2006. Managed multiple projects totaling $5M in budget; generated new customer service architectural systems for fledgling firms; reduced the cost of business operations by introducing the use of outsourcing firms. Successfully consolidated and a2 biology synoptic essay, streamlined business operations following the write my papwer, merger of Airtel and Vodafone. Led pilot teams to test new processes, anticipate crises and provide contingency solutions. Increased revenue by over 25% using a cross-functional team of financial, technical and business experts who analyzed and discovered a leak in a2 biology essay questions business operations while working on another project Honored with ‘Best Innovator Award’ for introducing web-based project management tools for write managing outsourcing firms and tracking project details. MBA (GPA: 3.8), University of London, London, 2005.

B Sc (GPA: 3.75), Hult University, London, 2001. PMI-Certified Project Management Professional (PMP), 2002.

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Extracorporeal membrane oxygenation (ECMO) for critically ill adults in the emergency department: history, current applications, and future directions. © Mosier et al. Help Write My Papwer? 2015. Published: 17 December 2015. Extracorporeal membrane oxygenation (ECMO) is a mode of how to write extracorporeal life support that augments oxygenation, ventilation and/or cardiac output via cannulae connected to a circuit that pumps blood through an oxygenator and back into the patient. Help My Papwer? ECMO has been used for decades to support cardiopulmonary disease refractory to conventional therapy.

While not robust, there are promising data for the use of ECMO in acute hypoxemic respiratory failure, cardiac arrest, and cardiogenic shock and the potential indications for ECMO continue to increase. Macro? This review discusses the existing literature on help write the potential use of ECMO in critically ill patients within the emergency department. Extracorporeal life support (ECLS) is a general term used to best letter, describe temporary support of my papwer cardiac or pulmonary function using mechanical devices. When using the “heart–lung machine” to completely bypass the cardiopulmonary circulation, it is referred to as cardiopulmonary bypass. When ECLS is used in the intensive care unit (ICU) or emergency department (ED) to augment oxygenation, ventilation, or cardiac output it is generally referred to as extracorporeal membrane oxygenation (ECMO).

As the science of willett ECLS has progressed internationally, ECLS use in United States ICUs has increased over 400 % since 2006 [ 1 ]. This has led to interest in potential earlier applications in the ED, and possibly even the help prehospital setting. Greatest Influence College? This review focuses on help write my papwer one modality of ECLS, ECMO, and describes the history of ECMO, common current applications, and important considerations related to ECMO use in adult ED patients. ECLS was initially developed in greatest college essay, the 1950s by John Gibbon as a means of oxygenating blood via a membrane oxygenator during prolonged operations on cardiopulmonary bypass [ 2 ]. Given the lack of an open reservoir of blood and extreme anticoagulation required with a traditional cardiopulmonary bypass circuit, ECMO presented a less complex and more sustainable option for treatment of refractory cardiovascular and respiratory failure outside the help operating room. Several reports were published demonstrating successful use in “shock-lung syndrome”, “adult capillary leak syndromes”, and cardiopulmonary failure in the late 1970s [ 3 , 4 ]. Best? In 1979, a randomized controlled trial conducted on adult patients with severe acute respiratory failure reported a 90 % mortality rate for patients in both groups [ 5 ]. Thus, enthusiasm stalled and over the next 30 years ECMO was used mostly for neonatal and write my papwer, pediatric patients with only a small number of college essay highly specialized centers pursuing ECMO in adult patients. Technological improvements and advances in other aspects of critical care have created an ECMO landscape that is very different from the early days of 90 % mortality. My Papwer? For patients with severe hypoxemic respiratory failure, the publication of the Conventional Ventilatory Support versus Extracorporeal Membrane Oxygenation for Severe Adult Respiratory Failure (CESAR) trial and several reports of improved survival in macro, patients with acute respiratory distress syndrome (ARDS) treated with ECMO during the H1N1 influenza pandemic have led to write my papwer, a significant expansion of ECMO use [ 6 – 9 ]. Recent data show promise when ECMO is used early in patients with cardiac arrest to augment traditional cardiopulmonary resuscitation in the form of buy cover letter extracorporeal cardiopulmonary resuscitation (ECPR) [ 10 – 15 ]. ECPR may play a role in help my papwer, the prehospital [ 16 ] or ED management of buy cover letter refractory cardiac arrest, cardiovascular collapse due to pulmonary embolism [ 17 ], hypothermia [ 18 ], drowning [ 19 ], overdoses [ 20 ], airway obstruction [ 21 ], and severe electrolyte abnormalities [ 22 ]. Veno-venous ECMO for severe acute respiratory failure. Acute respiratory failure due to potentially reversible processes such as ARDS or utilization as a bridge-to-transplant have become the help write most common indications for ECMO therapy in adults [ 23 ]. Synoptic Essay Questions? It is well recognized that positive pressure ventilation can have deleterious effects leading to ventilator-induced lung injury, oxidative stress, and further lung damage. Utilizing ECMO in write my papwer, these patients allows “lung rest” through more protective ventilator settings [ 24 ]. Initial randomized trials of ECMO for respiratory failure did not show a benefit compared with traditional ventilator methods [ 5 , 25 ]. In the best buy cover 1990s and 2000s, survival rates reported in case series with ECMO improved to 52–75 % [ 26 , 27 ]. During the H1N1 pandemic in which patients frequently developed severe ARDS with refractory hypoxemia, patients treated with ECMO showed survival rates as high as 79 % [ 7 , 9 , 28 , 29 ]. The first modern randomized controlled trial of ECMO for help adult patients with ARDS, the CESAR trial, was published in essay competition singapore, 2009. Help My Papwer? It evaluated outcomes in patients with severe ARDS transferred to an ECMO referral center versus patients treated with conventional therapy.

Although mortality at any point was not significantly different, the singapore study identified significantly higher 6-month survival rates in the group transferred to the ECMO referral center—of which only 75 % of the patients received ECMO—versus the control group that were not transferred [ 30 ]. My Papwer? Thus, it may have been other aspects of care at the ECMO center, not necessarily the rosemarie willett thesis ECMO itself, that led to improved outcomes. The Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome (EOLIA) trial is currently underway, evaluating early ECMO within 3 hours of my papwer initiation of mechanical ventilation for patients with refractory hypoxemia and severe ARDS [ 31 ]. A2 Biology Synoptic Questions? If this trial finds a benefit of early ECMO for ARDS, coordinating transfer to ECMO-capable referral centers directly from the ED for my papwer early initiation of ECMO support may become important for patient outcomes [ 32 ]. In addition to supporting oxygenation, ECMO may be a beneficial option in greatest influence college essay, patients with hypercapneic respiratory failure that are unable to be managed with mechanical ventilation [ 33 ]. Veno-arterial ECPR for cardiac arrest. Despite advances in management, outcomes for both in-hospital and out-of-hospital cardiac arrest remain poor. In-hospital cardiac arrest treated with conventional cardiopulmonary resuscitation (CPR) typically has a survival rate of 15–17 % and help write my papwer, out-of-hospital cardiac arrest (OHCA) survival is even lower at write macro, only 8–10 % [ 34 , 35 ]. Write My Papwer? The worst outcomes are in patients with prolonged time to return of spontaneous circulation. Prolonged cerebral hypoperfusion leads to significantly worse neurologic sequelae and early initiation of buy cover ECPR with veno-arterial (VA) ECMO may be a useful adjunct to reducing the interval time from arrest to restoration of cerebral perfusion. Data for in-hospital arrest are the most promising, likely due to the shorter interval from the onset of arrest to initiation of ECMO flow. Help Write My Papwer? While there are no randomized trials to date, observational studies have reported an paper, association between ECPR and improved survival. In a retrospective, single-center, propensity-matched analysis, Shin et al. Help Write? [ 12 ] showed improved survival with favorable neurologic outcome (Glasgow-Pittsburgh Cerebral Performance Category (CPC) score of 1 or 2) for patients with in-hospital arrest treated with ECPR versus conventional CPR (hazard ratio (HR) 0.17, 95 % confidence interval (CI) 0.04–0.68). Essay Questions? Chen et al. [ 11 ] found similar 30-day (HR 0.47, 95 % CI 0.28–0.77) and 1-year (HR 0.53, 95 % CI 0.33–0.83) survival for ECPR when compared with conventional CPR.

Both studies indicated improved outcomes when the write my papwer arrest was of cardiac origin. Another retrospective review of buy cover letter prolonged in-hospital arrests (15 minutes) or refractory shock after return of spontaneous circulation showed nearly half of the patients who survived had a CPC score of 1 or 2 with the use of ECPR [ 10 ]. Other observational studies have found variable improvements in mortality with the write use of ECPR [ 36 , 37 ]. How To Write Macro? A recent meta-analysis performed by Cardarelli et al. My Papwer? [ 38 ] in 135 patients from willett thesis 1990 to my papwer, 2007 showed a hospital survival rate to synoptic essay, discharge with ECPR of write 40 %. Reports from OHCA studies are not as robust, although there are dramatic reports of otherwise hopeless cases rescued by how to macro ECMO [ 39 ]. Write My Papwer? Haneya et al. [ 40 ] compared ECPR initiated in the ED for buy cover letter OHCA with ECPR initiated for in-hospital cardiac arrest, and found a survival rate of 42 % for in-hospital arrest patients versus only 15 % for OHCA patients. ECPR combined with therapeutic hypothermia and my papwer, intra-aortic balloon pump placement was recently shown to improve neurologic outcomes for OHCA patients with ventricular fibrillation or pulseless ventricular tachycardia. Willett Thesis? This study demonstrated survival with a favorable CPC score in 11.2 % of those with ECPR versus 2.6 % with conventional CPR at 6 months [ 14 ]. Help My Papwer? Similar results were reported in synoptic questions, a small observational pilot study in Australia combining mechanical compression devices, ECPR, and hypothermia for my papwer patients with refractory cardiac arrest. In this small study, 5 of 11 OHCA patients and paper, 9 of 15 in-hospital cardiac arrest patients survived, and favorable neurological outcome was achieved in half of the survivors [ 15 ]. For witnessed OHCA of write my papwer cardiac origin, ECPR has shown even greater improvements in neurologically favorable survival (29 % ECPR versus 8.9 % CPR) [ 13 ]. A2 Biology Synoptic Questions? A very promising recent observational study in 26 patients with refractory cardiac arrest, either in-hospital or OHCA, reported a favorable neurological survival rate of 54 % when ECPR was combined with a mechanical compression device and help write, therapeutic hypothermia [ 15 ]. However, these data have not been replicated and similar studies have reported survival rates ranging from 4–15 % [ 41 – 43 ]. When ECPR can be initiated rapidly, the essay outcomes for OHCA may be similar to those seen with in-hospital cardiac arrest patients [ 44 , 45 ]. Although there are no large prospective randomized trials and help my papwer, survival from refractory cardiac arrest is poor, ECPR may provide a tool to improve survival with good neurologic outcomes when initiated early in selected patients. While an optimistic estimate of survival from OHCA with the write use of ECPR may be in the 15–20 % range, the critical factor that determines success appears to be the duration from the onset of help write my papwer arrest to achieving ECMO flow.

This may be why in-hospital cardiac arrest studies have generally reported better outcomes [ 45 – 47 ]. Furthermore, the research volume of patients meeting optimal criteria for ECPR, including witnessed ventricular fibrillation/tachycardia with a short interval to initiation of CPR, refractory arrest despite optimal resuscitative efforts, and 75 years of age comprises a very small (10 %) subset of help my papwer all patients with OHCA [ 48 , 49 ]. Additionally, complication rates of ECPR remain high [ 43 , 50 , 51 ]. Currently the American Heart Association’s position is that evidence does not support a recommendation for ECPR, although it may be considered in highly specialized centers in greatest influence college, patients who have a potentially reversible disease and a short duration of cardiac arrest [ 52 ]. The recent Institute of Medicine report on cardiac arrest care states ECMO is an emerging technology that has promise in improving cardiac arrest care and should be developed and researched [ 53 ]. In addition to ECPR, ECMO may have a role in select patients with cardiogenic or septic shock [ 54 – 56 ], toxic ingestions [ 57 ], thyrotoxicosis [ 58 ], or trauma [ 59 ]. For patients with septic shock, high survival rates may be achievable, although survival rates are significantly diminished in the presence of multi-organ failure and in patients cannulated during cardiac arrest [ 55 , 60 ]. ECMO has shown promising results as a method of supporting hemodynamics in patients with cardiogenic shock due to acute myocardial infarction [ 61 ], massive pulmonary embolism [ 62 ] or myocarditis [ 63 ]. ECMO may be preferable to aortic balloon pumps as it can provide more robust biventricular support by increasing right ventricular drainage in addition to supporting gas exchange, and it can be employed quickly at the bedside. Help Write My Papwer? However, the downside of ECMO for cardiac support is that because of the retrograde aortic flow, left ventricular afterload and oxygen demand increase without the placement of a left ventricular drain. ECMO can serve as a bridge to recovery, device implantation, or cardiac transplantation. Small trials have shown improved survival rates in good paper, patients placed on ECMO as a bridge to a left ventricular assist device and subsequently to transplantation [ 64 ]. Several small studies have shown success in help my papwer, treating cardiogenic shock with ECMO, but there are no data comparing outcomes with ECMO versus alternative rescue modalities [ 65 ]. Arranging the initiation of ECMO may be a viable option in patients with known severe cardiac dysfunction in shock refractory to how to, conventional therapy in the ED. A successful ECLS program requires a significant multidisciplinary and organizational commitment to help write, ensure necessary resources and personnel [ 66 ]. Thesis? Hospitals with a higher volume of ECLS cases (30 cases/year) have shown improved mortality outcomes compared with hospitals with only a few cases per year (6) [ 67 ]. Initiating ECMO in a critically ill patient requires considerations related to equipment, blood bank capabilities, cannulation configuration, availability of necessary personnel, and coordination with the receiving critical care physicians. In a recent trial evaluating ECMO for OHCA, initiation of my papwer ECMO required two critical care physicians for cannulation, a third physician providing ultrasound guidance of cannula placement in a2 biology essay, the inferior vena cava, a fourth physician dedicated to leading the my papwer resuscitation, a nurse coordinator to initiate the willett thesis circuit, and a sixth person to help, infuse cold saline for intra-arrest hypothermia [ 15 ]. Additionally, while cannulation may be feasible by non-surgeons in the ED [ 68 ], close collaboration with surgeons is imperative due to risks of vascular injury requiring surgical repair. A successful ECLS program requires physicians, nurses, perfusionists, and respiratory therapists trained and competent in cannulation and management of the ECLS circuit to a2 biology essay, be available in sufficient numbers to provide 24/7 coverage. A streamlined exit strategy from the help write ED should be established, whether that includes transfer to the cardiac catheterization lab, ICU, or transfer to rosemarie willett, an ECMO receiving hospital.

Predetermined inclusion and exclusion criteria, as well as guidelines on help how and when to separate from ECMO in a patient who fails to improve are important to optimize outcomes and resource utilization. Finally, when considering initiating ECMO in research, the ED for a particular patient, current inpatient ECMO volume and capacity to help write my papwer, accommodate new patients must be considered. As a result, ECLS may not be a feasible option at many hospitals due to writing competition singapore, resource limitations. Local, regional, and inter-regional networks of hospitals with direct communication with the ECMO referral center that provides a mobile rescue team for cannulation and transport of help my papwer patients with critical cardiopulmonary failure may be the optimal solution to alleviate many of greatest influence these costly programmatic considerations. Veno-venous cannulation for ARDS. This chest X-ray demonstrates severe airspace disease in write, a patient with ARDS. The dual-lumen ECMO cannula ( arrows ) can be seen passing through the internal jugular vein, superior vena cava, and terminating in the inferior vena cava at the level of the paper resources hepatic vein. ECMO circuit components and flow. Flow through the ECMO circuit starts with the venous drainage cannula (1), which is propelled forward by the pressure gradient generated by the centrifugal pump head (2). The blood passes through the help my papwer oxygenator (3) and then returns to the patient in the outflow tubing back into influence, the right atrium (VV) or femoral artery (VA) (4).

Gas exchange is regulated by the amount of countercurrent “sweep” gas flowing through the oxygenator (5) and the blood is warmed by the thermoregulator attached to help, the circuit (6). Flow, hemoglobin, hematocrit and venous saturation can be continuously monitored by ultrasonic meters attached to the circuit (7 and 8) Percutaneous VA ECMO in adults most commonly involves femoral artery and vein cannulation where oxygenated blood is returned to the femoral artery and flows retrograde into competition, the aorta. Consequently, in the absence of write my papwer any native cardiac output, VA ECMO provides near complete cardiopulmonary bypass. In the presence of willett thesis native cardiac output, blood flow out help write, of the left ventricle mixes with retrograde ECMO return flow in the aorta. If there is no intrapulmonary shunt, the best buy cover native cardiac output is well oxygenated and this mixing is not detrimental. Help? However, if the patient’s lungs are failing (e.g., because of ARDS), blood flow from the native cardiac output is deoxygenated and competes with retrograde flowing oxygenated blood from the ECMO circuit. These competing flows mix somewhere in the aorta and can create differential hypoxemia (“North–south” syndrome) whereby poorly oxygenated blood preferentially perfuses the upper body, including the brain and heart, potentially leading to competition singapore, coronary and help, cerebral ischemia. Contraindications, complications, and ethical challenges. The decision to use ECMO requires a thoughtful risk–benefit evaluation. Best Buy Cover Letter? Contraindications are generally conditions that are known to be associated with a particularly poor outcome despite ECMO therapy.

Patients with severe neurologic injuries, intracranial hemorrhage, immunosuppression, irreversible multi-organ failure, untreatable malignancy, or those at an advanced age are typically poor ECMO candidates. Patients with aortic dissections or severe aortic regurgitation are not ECMO candidates due to the risks of propagating the dissection and over-distending the left ventricle, respectively. For patients with ARDS, relative contraindications include prolonged mechanical ventilation that has required injurious airway pressures. Help Write? For ECPR and cardiogenic shock, patients with unrecoverable heart disease, prolonged arrest time, and essay, those who are non-transplant or ventricular assist device candidates are poor ECMO candidates. If cannulated, these patients are relegated to a “bridge-to-nowhere”, which presents a complicated ethical dilemma in my papwer, that they cannot survive without ECMO but recovery is improbable and they are not candidates for essay questions definitive therapy.

Patients generally require anticoagulation while on ECMO and, while it is not an absolute contraindication, an inability to anticoagulate complicates both cannulation and long-term management strategies. Complication rates with ECMO are high. This is true during both cannulation and ongoing management [ 69 ]. Complications include hemorrhage, stroke, limb ischemia, thrombosis, and help my papwer, infection from the indwelling lines/tubes. Data show at least one significant complication occurs in over half of best letter patients on ECMO [ 65 ], with bleeding (30–40 %) [ 26 , 51 ] and infection (31 %) [ 51 ] being the most common. Hemorrhagic complications most commonly occur at the cannulation or surgical sites themselves and are generally related to anti-coagulation, of which VA ECMO requires more aggressive anticoagulation due to help my papwer, the risk of arterial thrombosis. VA cannulation carries a high risk of arterial injury—recently reported in 18 % of good research resources patients requiring VA ECMO, with most of the help write my papwer injuries requiring surgical repair [ 70 ]. Neurologic complications such as intracranial hemorrhage or infarct are also well-recognized and can be devastating. Other complications include hemolysis, pulmonary edema, and letter, lower extremity ischemia from occlusion of the arterial flow with placement of the arterial cannula, which can be prevented with the routine placement of an antegrade arterial cannula to my papwer, that limb. Little is known about long-term complications and quality of life in adult patients who have undergone ECMO. Research Paper? While there are many anecdotal cases of complete recovery from critical illness in ECMO survivors, some studies report neurologic injury and long-term neurocognitive abnormalities in over 50 % of help write my papwer cases [ 71 , 72 ]. In addition, ECMO survivors may experience a poor quality of life [ 73 , 74 ], anxiety, depression, and post-traumatic stress disorder [ 8 , 74 ]. ICU lengths of stay tend to be long in ECMO patients [ 26 , 74 ] and essay competition, their costs are generally much higher than patients receiving conventional therapy [ 75 ]. The challenges of complications, cost, and resource utilization, when taken together with the potential of creating a bridge-to-nowhere situation for some patients and lack of high-quality evidence, create an help write my papwer, ethical obligation to consider the risks and benefits very carefully when considering ECMO in paper, a patient’s treatment plan. Since its advent in the 1950s, ECLS has gone from the operating room to a promising rescue modality for cardiopulmonary failure in the ICU and beyond.

With expanding potential indications and help, improving outcomes, there is significant interest in the early application of buy cover ECMO in help write my papwer, the ED, yet significant hurdles still exist. These include lack of definitive data on write patient selection, complication rates, functional outcomes and help, survival as well as resource utilization and economic costs. Greatest Influence College? The H1N1 pandemic, combined with improvements in help write my papwer, general critical care, brought modern and improved ECMO technology into the limelight with good outcomes in the treatment of severe acute respiratory failure. Combined with recent data in patients with cardiac arrest and shock that show promising trends, there appears to be potential for competition singapore the early application of ECLS to help my papwer, patients in the ED. Write Macro? Currently, there are no data to support ECMO as anything other than a rescue therapy in experienced centers at this time. Emergency physicians should consider early transfer to a specialized center in the select patients in which ECMO has shown benefit.

Continuing research will likely spur further expansion of ECMO with increased utilization occurring in the ED and possibly even the prehospital setting. However, we encourage a cautious and evidence-based approach to help write, future applications of ECMO prior to write macro, widespread adoption given the my papwer logistical and ethical challenges of this technology that has the potential to outpace the supporting data. Acute respiratory distress syndrome. Conventional Ventilatory Support versus Extracoporeal Membrane Oxygenation for Severe Adult Respiratory Failure. Cerebral Performance Category. Extracorporeal life support. Extracorporeal membrane oxygenation. Extracorporeal cardiopulmonary resuscitation. Intensive care unit. Out-of-hospital cardiac arrest.

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and best buy cover letter, the source, provide a link to help write my papwer, the Creative Commons license, and how to macro, indicate if changes were made. Help? The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/ ) applies to the data made available in this article, unless otherwise stated. The authors declare that they have no competing interests. All authors contributed to the literature review, manuscript preparation and approval of the best buy cover letter final draft. J.M.M. is a dual-trained physician in help write, emergency medicine and critical care and associate medical director of adult ECMO services at buy cover, the University of Arizona. He is a member of the my papwer Arizona Emergency Medicine Research Center and the Arizona Respiratory Center. C.D.H. is rosemarie a dual-trained physician in emergency medicine and write my papwer, critical care at the University of Arizona. S.P.W. is a dual-trained physician in emergency medicine and critical care at rosemarie thesis, the University of Michigan.

K.J.G. is an associate professor of help write my papwer emergency medicine, internal medicine, and anesthesiology at the University of Michigan. He serves as the chief of the division of emergency critical care, medical director of the emergency critical care center, intensivist in how to write macro, the Cardiovascular ICU, and help, a core investigator in the Michigan Center for Integrative Research in rosemarie willett thesis, Critical Care (MCIRCC). Y.R. is the medical director of adult ECMO services at help write, the University of research Arizona. Help My Papwer? R.M. is the synoptic essay questions medical director of the pediatric ICU and ECMO services at the University of Arizona. D.W.S. is a Professor and Distinguished Chair of Emergency Medicine, Co-Director of write my papwer Emergency Medical Systems Research and the Associate Director of the Arizona Emergency Medicine Research Center at the University of Arizona. Sauer CM, Yuh DD, Bonde P. Extracorporeal membrane oxygenation use has increased by 433 % in adults in the United States from 2006 to 2011.

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